Prior art covers two distinct propositions: 1) section 102 invalidating prior art is a single reference that includes every limitation of a patent claim; and 2) section 103 invalidating prior art is a combination of one or more references that, taken together, teach or disclose every limitation of a patent claim.
The emphases in the previous statement are significant. It is also important to know that each patent claim represents a separate invention, so it is unusual to invalidate an entire patent with multiple claims based on a single prior art reference.
Appeals for prior art should be clear about just which patent claim they are focused on. In particular, such appeals should include any special definitions for claim terms that are specifically defined in the patent specification or previously interpreted by the Court (in a Markman Order).
This patent forum will develop more detailed requirements for formulating such requests as time goes on. But the description given above is a good start.